Anti-CDCA7 Antibody

Boster Bio Anti-CDCA7 Antibody (Catalog # A07777) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator.<br><br>Prescott J.E., J. Biol. Chem. 276:48276-48284(2001).<br>Ota T., Nat. Genet. 36:40-45(2004).<br>Hillier L.W., Nature 434:724-731(2005).

Synonyms

Cell division cycle-associated protein 7; Protein JPO1; CDCA7; JPO1

Gene Name

CDCA7

UniProt

Q9BWT1

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human CDCA7.

Clonality

Polyclonal

Tissue Specificity

Ubiquitous with higher level in thymus and small intestine. Overexpressed in a large number of tumors, in blood from patients with acute myelogenous leukemia (AML) and in chronic myelogenous leukemia (CML) blast crisis. .

Applications

Field of Research

Cancer, Epigenetics and Nuclear Signaling, Transcription, Tumor Biomarkers

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Molecular Weight

42573 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Cell division cycle-associated protein 7

Subcellular Location

Nucleus. Cytoplasm. Predominantly nuclear with some expression also seen in the cytoplasm. Predominantly cytoplasmic when phosphorylated at Thr-163.

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