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Anti-p50 Dynamitin DCTN2 Antibody

Boster Bio Anti-p50 Dynamitin DCTN2 Antibody (Catalog # A07698) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.<br><br>Scott S. Grieshaber, J. Cell Sci., Sep 2003; 116: 3793. <br>Janis K. Burkhardt, J. Cell Biol., Oct 1997; 139: 469. <br>Karin A. Melkonian, J. Biol. Chem., Apr 2007; 10.1074.<br>Lili Yue, J. Biol. Chem., Jul 2000; 275: 23948.

Synonyms

Dynactin subunit 2;50 kDa dynein-associated polypeptide; Dynactin complex 50 kDa subunit; DCTN-50; p50 dynamitin; DCTN2; DCTN50

Gene Name

DCTN2

UniProt

Q13561

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human p50 dynamitin.

Clonality

Polyclonal

Applications

WB

Field of Research

Cell Biology, Cell Cycle, Cell Division, Cytoskeleton, Cytoskeleton/ECM, Dynein, Motor Proteins, Signal Transduction, Spindle

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.

Molecular Weight

44231 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07698

Product MSDS

https://www.bosterbio.com/msds?sku=A07698

Other Gene Names

Dynactin subunit 2

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Membrane ; Peripheral membrane protein .

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