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Anti-ARL2BP Antibody

Boster Bio Anti-ARL2BP Antibody (Catalog # A07607) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.<br><br>Sharer J.D., J. Biol. Chem. 274:27553-27561(1999).<br>The MGC Project Team; Genome Res. 14:2121-2127(2004).<br>Van Valkenburgh H., J. Biol. Chem. 276:22826-22837(2001)

Synonyms

ADP-ribosylation factor-like protein 2-binding protein; ARF-like 2-binding protein; ARL2-binding protein; Binder of ARF2 protein 1; ARL2BP; BART, BART1

Gene Name

ARL2BP

UniProt

Q9Y2Y0

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human ARL2BP.

Clonality

Polyclonal

Tissue Specificity

Expressed in retina pigment epithelial cells (at protein level) . Widely expressed. .

Applications

WB

Field of Research

G Protein Signaling, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. .

Molecular Weight

18822 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

ADP-ribosylation factor-like protein 2-binding protein

Subcellular Location

Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, cilium basal body. The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria (By similarity) . Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules. In retina photoreceptor cells, localized in the distal connecting cilia, basal body, ciliary-associated centriole, and ciliary rootlet. Interaction with ARL2 may be required for cilia basal body localization. .

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