Anti-CNTN6/Contactin 6 Antibody
Boster Bio Anti-CNTN6/Contactin 6 Antibody (Catalog # A07585-1) . Tested in WB applications. This antibody reacts with Human.
Product Specifications
Background
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination By similarity.<br><br>Kamei Y., J. Neurosci. Res. 51:275-283(1998).<br>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br>Mayya V., Sci. Signal. 2:RA46-RA46(2009).
Synonyms
Contactin-6; Neural recognition molecule NB-3; hNB-3; CNTN6
Gene Name
CNTN6
UniProt
Q9UQ52
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from internal of human CNTN6.
Clonality
Polyclonal
Tissue Specificity
Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
Applications
WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Dilution
Western blotting: 1:500~1:3000
Form
Liquid
Function
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination (By similarity) . .
Molecular Weight
113956 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Contactin-6
Subcellular Location
Cell membrane ; Lipid-anchor, GPI-anchor .
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