Anti-IL-26 Antibody
Boster Bio Anti-IL-26 Antibody catalog # A07565. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Interleukin-26; IL-26; Protein AK155; IL26; AK155
Gene Name
IL26
UniProt
Q9NPH9
Host
Rabbit
Reactivity
Human
Immunogen
Synthesized peptide derived from Interleukin-26 at AA range: 21-70
Tissue Specificity
Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T-cells including Th17 inflammatory T-cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level) . .
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin. .
Molecular Weight
19843 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Interleukin-26
Subcellular Location
Secreted .
Curated Selection
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