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Anti-MBTPS2/S2P Antibody

Boster Bio Anti-MBTPS2/S2P Antibody (Catalog# A07369-1) . Tested in IF, ICC, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

MBTPS2; S2P; Membrane-bound transcription factor site-2 protease; Endopeptidase S2P; Sterol regulatory element-binding proteins intramembrane protease; SREBPs intramembrane protease

Gene Name

MBTPS2

UniProt

O43462

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human MBTPS2. Immunogen sequence location: 301-350

Clonality

Polyclonal

Tissue Specificity

Expressed in heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

Applications

IF, ICC, ELISA

Field of Research

Cardiovascular, Cell Biology, Cholesterol Metabolism, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathways, Metabolism, Pathways and Processes, Proteolysis/Ubiquitin, Proteolytic Enzymes, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Intramembrane proteolysis of sterol-regulatory element- binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.

Molecular Weight

57444 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Membrane-bound transcription factor site-2 protease

Subcellular Location

Membrane; Multi-pass membrane protein. Cytoplasm.

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