Anti-GCN5 KAT2A Antibody
Boster Bio Anti-GCN5 KAT2A Antibody catalog # A07210. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Histone acetyltransferase KAT2A;2.3.1.48; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; HsGCN5; Lysine acetyltransferase 2A; STAF97; KAT2A; GCN5, GCN5L2, HGCN5
Gene Name
KAT2A
UniProt
Q92830
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GCN5L2. AA range:691-740
Tissue Specificity
Expressed in all tissues tested, with most abundant expression in ovary.
Applications
WB
Purification
Immunogen affinity purified
Dilution
WB, 1:500-1:2000
Form
Liquid
Function
Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. Also acetylates non- histone proteins, such as CEBPB (PubMed:17301242) . Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat's transactivating activity and may help inducing chromatin remodeling of proviral genes. .
Molecular Weight
93926 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Histone acetyltransferase KAT2A
Subcellular Location
Nucleus .
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