Anti-BMP-10 Antibody
Boster Bio Anti-BMP-10 Antibody catalog # A06968-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Bone morphogenetic protein 10; BMP-10; BMP10
Gene Name
BMP10
UniProt
O95393
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from BMP-10 at AA range: 361-410
Tissue Specificity
Detected in mammary epithelia (at protein level) . .
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. .
Molecular Weight
48047 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A06968-1
Product MSDS
https://www.bosterbio.com/msds?sku=A06968-1
Other Gene Names
Bone morphogenetic protein 10
Subcellular Location
Secreted .
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