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Anti-BMP-10 Antibody

Boster Bio Anti-BMP-10 Antibody catalog # A06968-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Bone morphogenetic protein 10; BMP-10; BMP10

Gene Name

BMP10

UniProt

O95393

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from BMP-10 at AA range: 361-410

Tissue Specificity

Detected in mammary epithelia (at protein level) . .

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines. .

Molecular Weight

48047 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Bone morphogenetic protein 10

Subcellular Location

Secreted .

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