Anti-CysLTR2/Cyslt2 Antibody
Boster Bio Anti-CysLTR2/Cyslt2 Antibody catalog # A06895. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
Cysteinyl leukotriene receptor 2; CysLTR2; G-protein coupled receptor GPCR21; hGPCR21; G-protein coupled receptor HG57; HPN321; CYSLTR2; CYSLT2, CYSLT2R; PSEC0146
Gene Name
CYSLTR2
UniProt
Q9NS75
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human CLTR2. AA range:281-330
Tissue Specificity
Widely expressed, with highest levels in the heart, placenta, spleen, peripheral blood leukocytes and adrenal gland. In lung, expressed in the interstitial macrophages, and slightly in smooth muscle cells.
Applications
WB
Purification
Immunogen affinity purified
Dilution
WB, 1:500-1:2000
Form
Liquid
Function
Receptor for cysteinyl leukotrienes. The response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system. Stimulation by BAY u9773, a partial agonist, induces specific contractions of pulmonary veins and might also have an indirect role in the relaxation of the pulmonary vascular endothelium. The rank order of affinities for the leukotrienes is LTC4 = LTD4 >> LTE4.
Molecular Weight
39635 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Cysteinyl leukotriene receptor 2
Subcellular Location
Cell membrane; Multi-pass membrane protein.
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