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Anti-LARG ARHGEF12 Antibody

Boster Bio Anti-LARG ARHGEF12 Antibody catalog # A06802-1. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

Rho guanine nucleotide exchange factor 12; Leukemia-associated RhoGEF; ARHGEF12; KIAA0382, LARG

Gene Name

ARHGEF12

UniProt

Q9NZN5

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human ARHGEF12. AA range:449-498

Tissue Specificity

Ubiquitously expressed. Isoform 2 is found in jejunum and testis.

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) . Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. .

Molecular Weight

173232 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Rho guanine nucleotide exchange factor 12

Subcellular Location

Cytoplasm . Membrane . Translocated to the membrane upon stimulation. .

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