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Anti-AMOTL1/Angiomotin Like 1 Antibody

Boster Bio Anti-AMOTL1/Angiomotin Like 1 Antibody (Catalog # A06741) . Tested in IHC applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.<br><br>Bratt A., Gene 298:69-77(2002).<br>Bratt A., Gene 310:231-231(2003).<br>Yu L.-R., J. Proteome Res. 6:4150-4162(2007).

Synonyms

Angiomotin-like protein 1; AMOTL1

Gene Name

AMOTL1

UniProt

Q8IY63

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from internal of human AMOTL1.

Clonality

Polyclonal

Applications

IHC

Field of Research

Cardiovascular, Cell Adhesion, Cytoskeleton/ECM, Signal Transduction, Tight Junctions, Vasculature

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunohistochemistry: 1:50~1:100

Form

Liquid

Function

Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. .

Molecular Weight

106574 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06741

Product MSDS

https://www.bosterbio.com/msds?sku=A06741

Other Gene Names

Angiomotin-like protein 1

Subcellular Location

Cell junction, tight junction .

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