What is the catalog number for Anti-MBTPS1 Antibody?

The catalog number for Anti-MBTPS1 Antibody is A06735.

Is Anti-MBTPS1 Antibody in stock?

Anti-MBTPS1 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-MBTPS1 Antibody?

The safety data sheet for Anti-MBTPS1 Antibody is available here: https://www.bosterbio.com/msds?sku=A06735.

Anti-MBTPS1 Antibody

Boster Bio Anti-MBTPS1 Antibody (Catalog # A06735) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.<br><br>Nakajima T., J. Hum. Genet. 45:212-217(2000).<br>Nagase T., DNA Res. 2:37-43(1995).<br>Bechtel S., BMC Genomics 8:399-399(2007).

Synonyms

Membrane-bound transcription factor site-1 protease;3.4.21.112; Endopeptidase S1P; Subtilisin/kexin-isozyme 1; SKI-1; MBTPS1; KIAA0091, S1P, SKI1

Gene Name

MBTPS1

UniProt

Q14703

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from C-terminal of human MBTPS1.

Clonality

Polyclonal

Tissue Specificity

Widely expressed.

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs) . Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg- Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes. .

Molecular Weight

117749 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Membrane-bound transcription factor site-1 protease

Subcellular Location

Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Golgi apparatus membrane ; Single-pass type I membrane protein . May sort to other organelles, including lysosomal and/or endosomal compartments.