Anti-TLK2 Antibody
Boster Bio Anti-TLK2 Antibody catalog # A06645. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Serine/threonine-protein kinase tousled-like 2;2.7.11.1; HsHPK; PKU-alpha; Tousled-like kinase 2; TLK2
Gene Name
TLK2
UniProt
Q86UE8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human TLK2. AA range:191-240
Tissue Specificity
Ubiquitous. Detected in placenta, fetal liver, kidney, pancreas, heart and skeletal muscle. Highly expressed in testis. Detected in spleen, thymus, colon, ovary, small intestine, prostate and peripheral blood leukocytes. .
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly. Negative regulator of amino acid starvation-induced autophagy. .
Molecular Weight
87661 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Serine/threonine-protein kinase tousled-like 2
Subcellular Location
Nucleus. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton. Colocalizes with the cytoplasmic intermediate filament system during the G1 phase of the cell cycle. Present in the perinuclear region at S phase and in the nucleus at late G2.
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