Anti-GluR8 GRM8 Antibody
Boster Bio Anti-GluR8 GRM8 Antibody (Catalog # A06589) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<br><br>Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 - 848.<br>RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 - 1339.<br>Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 - 9808.<br>V. Bruno, J. Neurosci., Sep 2000; 20: 6413.
Synonyms
Metabotropic glutamate receptor 8; mGluR8; GRM8; GPRC1H, MGLUR8
Gene Name
GRM8
UniProt
O00222
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from human GluR8.
Clonality
Polyclonal
Applications
WB, IHC
Field of Research
Receptors / Channels
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. .
Molecular Weight
101741 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Other Gene Names
Metabotropic glutamate receptor 8
Subcellular Location
Cell membrane; Multi-pass membrane protein.
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