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Anti-GluR8 GRM8 Antibody

Boster Bio Anti-GluR8 GRM8 Antibody (Catalog # A06589) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.<br><br>Patrick. M. Downey, J Biomol Screen, Dec 2005; 10: 841 - 848.<br>RJ Wenthold, J. Biol. Chem., Jan 1994; 269: 1332 - 1339.<br>Toshiaki Watanabe, Cancer Res., Oct 2006; 66: 9804 - 9808.<br>V. Bruno, J. Neurosci., Sep 2000; 20: 6413.

Synonyms

Metabotropic glutamate receptor 8; mGluR8; GRM8; GPRC1H, MGLUR8

Gene Name

GRM8

UniProt

O00222

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human GluR8.

Clonality

Polyclonal

Applications

WB, IHC

Field of Research

Receptors / Channels

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. .

Molecular Weight

101741 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06589

Product MSDS

https://www.bosterbio.com/msds?sku=A06589

Other Gene Names

Metabotropic glutamate receptor 8

Subcellular Location

Cell membrane; Multi-pass membrane protein.

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