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Anti-PRKX Antibody

Boster Bio Anti-PRKX Antibody (Catalog# A06585-1) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

PRKX; PKX1; cAMP-dependent protein kinase catalytic subunit PRKX; PrKX; Protein kinase X; Protein kinase X-linked; Serine/threonine-protein kinase PRKX; Protein kinase PKX1

Gene Name

PRKX

UniProt

P51817

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human PRKX. Immunogen sequence location: 251 - 300

Clonality

Polyclonal

Tissue Specificity

Widely expressed (at protein level) . Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.

Molecular Weight

40896 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A06585-1

Product MSDS

https://www.bosterbio.com/msds?sku=A06585-1

Fragment

Rabbit IgG

Other Gene Names

CAMP-dependent protein kinase catalytic subunit PRKX

Subcellular Location

Cytoplasm. Nucleus. cAMP induces nuclear translocation.

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