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Anti-GluR4 GRM4 Antibody

Boster Bio Anti-GluR4 GRM4 Antibody (Catalog # A06552) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.<br><br>Susana Santos Correia, J. Biol. Chem., Feb 2003; 278: 6307 - 6313.<br>Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224.<br>Maxim Mokin, J Neurophysiol, Jan 2006; 95: 215 - 224.<br>Peyman Golshani, PNAS, Mar 2001; 98: 4172.

Synonyms

Metabotropic glutamate receptor 4; mGluR4; GRM4; GPRC1D, MGLUR4

Gene Name

GRM4

UniProt

Q14833

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from human GluR4.

Clonality

Polyclonal

Tissue Specificity

Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver. .

Applications

WB, IHC

Field of Research

Amino Acids, G Protein Signaling, Neuroscience, Neurotransmission, Neurotransmitter, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity. .

Molecular Weight

101868 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Metabotropic glutamate receptor 4

Subcellular Location

Cell membrane ; Multi-pass membrane protein .

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