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Anti-AMID AIFM2 Antibody

Boster Bio Anti-AMID AIFM2 Antibody catalog # A06541-1. Tested in WB applications. This antibody reacts with Human, Monkey, Mouse.

Product Specifications

Synonyms

Apoptosis-inducing factor 2;1.-.-.-; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; p53-responsive gene 3 protein; AIFM2; AMID, PRG3

Gene Name

AIFM2

UniProt

Q9BRQ8

Host

Rabbit

Reactivity

Human, Mouse, Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human AIFM2. AA range:141-190

Tissue Specificity

Detected in most normal tissues as two transcripts of 1.8 and 4.0 kb in length, respectively. Highly expressed in heart, moderately in liver and skeletal muscles, and expressed at low levels in placenta, lung, kidney, and pancreas. Both transcripts expressed following p53/TP53 induction. The shorter 1.8 kb transcript seems to be the major transcript in EB1 colon cancer cells. .

Applications

WB

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

Oxidoreductase, which may play a role in mediating a p53/TP53-dependent apoptosis response. Probable oxidoreductase that acts as a caspase-independent mitochondrial effector of apoptotic cell death. Binds to DNA in a sequence-independent manner. May contribute to genotoxin-induced growth arrest. .

Molecular Weight

40527 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

Apoptosis-inducing factor 2

Subcellular Location

Cytoplasm. Mitochondrion outer membrane. Membrane ; Lipid-anchor .

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