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Anti-mGluR6 GRM6 Antibody

Boster Bio Anti-mGluR6 GRM6 Antibody (Catalog# A06163-1) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

GRM6; GPRC1F; MGLUR6; Metabotropic glutamate receptor 6; mGluR6

Gene Name

GRM6

UniProt

O15303

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human mGluR6. Immunogen sequence location: 828-877

Clonality

Polyclonal

Tissue Specificity

Detected in melanocytes.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Amino Acids, G Protein Signaling, Neuroscience, Neurotransmission, Neurotransmitter, Receptors / Channels, Signal Transduction, Signaling Pathway

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity) . Signaling stimulates TRPM1 channel activity and Ca (2+) uptake. Required for normal vision.

Molecular Weight

95468 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Metabotropic glutamate receptor 6

Subcellular Location

Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane.

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