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Anti-SR-1D HTR1D Antibody

Boster Bio Anti-SR-1D HTR1D Antibody catalog # A06046. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

5-hydroxytryptamine receptor 1D;5-HT-1D;5-HT1D; Serotonin 1D alpha receptor;5-HT-1D-alpha; Serotonin receptor 1D; HTR1D; HTR1DA, HTRL

Gene Name

HTR1D

UniProt

P28221

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from SR-1D . at AA range: 120-200

Clonality

Polyclonal

Tissue Specificity

Detected in brain neocortex and caudate nucleus (at protein level) . .

Applications

ELISA, IHC-P, WB

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

G-protein coupled receptor for 5-hydroxytryptamine (serotonin) . Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitters. May play a role in vasoconstriction. .

Molecular Weight

41907 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

5-hydroxytryptamine receptor 1D

Subcellular Location

Cell membrane ; Multi- pass membrane protein .

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