Anti-KCNK4 (TRAAK) Antibody

Potassium channel subfamily K member 4; TWIK-related arachidonic acid-stimulated potassium channel protein ; TRAAK ; Two pore potassium channel KT4.1; Two pore K (+) channel KT4.1; KCNK4; TRAAK

Voltage-insensitive potassium channel (PubMed:22282805) . Channel opening is triggered by mechanical forces that deform the membrane (PubMed:22282805, PubMed:25471887, PubMed:25500157) . Channel opening is triggered by raising the intracellular pH to basic levels (By similarity) . The channel is inactive at 24 degrees Celsius (in vitro) ; raising the temperature to 37 degrees Celsius increases the frequency of channel opening, with a further increase in channel activity when the temperature is raised to 42 degrees Celsius (By similarity) . Plays a role in the perception of pain caused by heat (By similarity) . Plays a role in the sensory perception of pain caused by pressure (By similarity) . .