Anti-UBE2T/Hspc150 Antibody
Boster Bio Anti-UBE2T/Hspc150 Antibody catalog # A05874-1. Tested in WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Ubiquitin-conjugating enzyme E2 T;2.3.2.23 ; Cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; Ubiquitin carrier protein T; Ubiquitin-protein ligase T; UBE2T; HSPC150, PIG50
Gene Name
UBE2T
UniProt
Q9NPD8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human UBE2T. AA range:121-170
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC) -induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. .
Molecular Weight
22521 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Ubiquitin-conjugating enzyme E2 T
Subcellular Location
Nucleus . Accumulates to chromatin.
Curated Selection
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