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Anti-PHLA1 PHLDA1 Antibody

Boster Bio Anti-PHLA1 PHLDA1 Antibody (Catalog # A05823) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.<br><br>Kuske M.D., Cytogenet. Cell Genet. 89:1-1(2000).<br>Neef R., Cancer Res. 62:5920-5929(2002).<br>Hinz T., Cell. Signal. 13:345-352(2001).

Synonyms

Pleckstrin homology-like domain family A member 1; Apoptosis-associated nuclear protein; Proline- and glutamine-rich protein; PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated gene 51 protein; PHLDA1; PHRIP, TDAG51

Gene Name

PHLDA1

UniProt

Q8WV24

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human PHLA1.

Clonality

Polyclonal

Tissue Specificity

Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level) . .

Applications

WB

Field of Research

Apoptosis, Associated Proteins, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Intracellular

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation. .

Molecular Weight

45016 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Pleckstrin homology-like domain family A member 1

Subcellular Location

Cytoplasm . Cytoplasmic vesicle . Nucleus, nucleolus . Colocalizes with intracellular vesicles. .

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