Anti-PPP2R2B Antibody

Boster Bio Anti-PPP2R2B Antibody (Catalog # A05805) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity By similarity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance By similarity.<br><br>Mayer R.E., Biochemistry 30:3589-3597(1991) [PubMed: 1849734].<br>Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].<br>Schmutz J., Nature 431:268-274(2004) [PubMed: 15372022].

Synonyms

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; PP2A subunit B isoform B55-beta; PP2A subunit B isoform PR55-beta; PP2A subunit B isoform R2-beta; PP2A subunit B isoform beta; PPP2R2B

Gene Name

PPP2R2B

UniProt

Q00005

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human PPP2R2B.

Clonality

Polyclonal

Tissue Specificity

Brain.

Applications

Field of Research

Neurodegenerative Disease, Neurology Process, Neuroscience, Protein Phosphorylation, Ser/Thr Phosphatases, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Molecular Weight

51710 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

Subcellular Location

Isoform 1: Cytoplasm . Cytoplasm, cytoskeleton . Membrane .

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