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Anti-DNAJB11/Erdj3 Antibody

Boster Bio Anti-DNAJB11/Erdj3 Antibody (Catalog # A05802) . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.<br><br>Ohtsuka K., Cell Stress Chaperones 5:98-112(2000).<br>Yu M., J. Biol. Chem. 275:24984-24992(2000).<br>Bies C., Biol. Chem. 385:389-395(2004).

Synonyms

DnaJ homolog subfamily B member 11; APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4; DNAJB11; EDJ, ERJ3, HDJ9; PSEC0121, UNQ537/PRO1080

Gene Name

DNAJB11

UniProt

Q9UBS4

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human DNAJB11.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. .

Applications

WB, IHC

Field of Research

Chaperones, Heat Shock Proteins, Protein Trafficking, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. .

Molecular Weight

40514 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

DnaJ homolog subfamily B member 11

Subcellular Location

Endoplasmic reticulum lumen . Associated with the ER membrane in a C-terminally epitope- tagged construct.

Frequently Asked Questions

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