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Anti-ERN2 Antibody

Boster Bio Anti-ERN2 Antibody (Catalog# A05659-1) . Tested in IHC-P, IF, ICC, ELISA applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

ERN2; IRE2; Serine/threonine-protein kinase/endoribonuclease IRE2; Endoplasmic reticulum-to-nucleus signaling 2; Inositol-requiring protein 2; hIRE2p; Ire1-beta; IRE1b

Gene Name

ERN2

UniProt

Q76MJ5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A peptide derived from human ERN2. Immunogen sequence location: 841-890

Clonality

Polyclonal

Applications

IHC-P, IF, ICC, ELISA

Field of Research

Apoptosis, Cell Biology, DNA/RNA, Epigenetics and Nuclear Signaling, Intracellular, Kinases, Protein Phosphorylation, Ser/Thr Kinases, Signal Transduction, Translation

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.

Molecular Weight

102480 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Serine/threonine-protein kinase/endoribonuclease IRE2

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

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