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Anti-SEC16A Antibody

Boster Bio Anti-SEC16A Antibody (Catalog# A05622) . Tested in IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

SEC16A; KIAA0310; SEC16; SEC16L; Protein transport protein Sec16A; SEC16 homolog A

Gene Name

SEC16A

UniProt

O15027

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human SEC16A. Immunogen sequence location: 1013 - 1062

Clonality

Polyclonal

Tissue Specificity

Ubiquitous. Expressed at higher levels in the pancreas.

Applications

IHC-P, IF (paraffin), ELISA

Field of Research

Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic reticulum (tER) organization.

Molecular Weight

233517 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Protein transport protein Sec16A

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. SAR1A activity is required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation.

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