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Anti-MED13L/Thrap2 Antibody

Boster Bio Anti-MED13L/Thrap2 Antibody (Catalog# A05593-1) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Rat, Mouse.

Product Specifications

Synonyms

POLDIP3; KIAA1649; PDIP46; Polymerase delta-interacting protein 3;46 kDa DNA polymerase delta interaction protein; p46; S6K1 Aly/REF-like target; SKAR

Gene Name

MED13L

UniProt

Q9BY77

Host

Rabbit

Reactivity

Human, Rat, Mouse

Immunogen

A peptide derived from human MED13L. Immunogen sequence location: 449-498

Clonality

Polyclonal

Tissue Specificity

Highly expressed in brain (cerebellum), heart (aorta), skeletal muscle, kidney, placenta and peripheral blood leukocytes.Highly expressed in fetal brain.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Epigenetics and Nuclear Signaling, Mediator Complex, Nuclear, Pol II Transcription, Polymerase Associated Factors, Signaling Pathways, Stem Cells, Transcription

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Molecular Weight

242602 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Mediator of RNA polymerase II transcription subunit 13-like

Subcellular Location

Nucleus.

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