Anti-CYP8B1 Antibody
Boster Bio Anti-CYP8B1 Antibody catalog # A05518-1. Tested in ELISA, IHC-P, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase;1.14.18.8 ;7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase; CYPVIIIB1; Cytochrome P450 8B1; Sterol 12-alpha-hydroxylase; CYP8B1; CYP12
Gene Name
CYP8B1
UniProt
Q9UNU6
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 8B1. AA range:371-420
Clonality
Polyclonal
Tissue Specificity
Liver.
Applications
ELISA, IHC-P, WB
Purification
Immunogen affinity purified
Concentration
1 mg/ml
Form
Liquid
Function
Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha- hydroxylated C27 steroids. .
Molecular Weight
58068 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase
Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein. Microsome membrane; Single-pass membrane protein.
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