What is the catalog number for Anti-NEIL3/Nei3 Antibody?

The catalog number for Anti-NEIL3/Nei3 Antibody is A05497-1.

What sizes are available for Anti-NEIL3/Nei3 Antibody?

Anti-NEIL3/Nei3 Antibody is available in the following size(s): 100 µL.

Is Anti-NEIL3/Nei3 Antibody in stock?

Anti-NEIL3/Nei3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-NEIL3/Nei3 Antibody?

The safety data sheet for Anti-NEIL3/Nei3 Antibody is available here: https://www.bosterbio.com/msds?sku=A05497-1.

Anti-NEIL3/Nei3 Antibody

Boster Bio Anti-NEIL3/Nei3 Antibody catalog # A05497-1. Tested in WB applications. This antibody reacts with Human, Mouse.

Product Specifications

Synonyms

Endonuclease 8-like 3;3.2.2.-;4.2.99.18; DNA glycosylase FPG2; DNA glycosylase/AP lyase Neil3; Endonuclease VIII-like 3; Nei-like protein 3; NEIL3

Gene Name

NEIL3

UniProt

Q8TAT5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human NEIL3. AA range:491-540

Clonality

Polyclonal

Tissue Specificity

Expressed in keratinocytes and embryonic fibroblasts (at protein level) . Also detected in thymus, testis and fetal lung primary fibroblasts. .

Applications

WB

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA) . In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5- OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA- (apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair. .