Rp-8-pCPT-cGMPS
Product Specifications
UNSPSC Description
Rp-8-pCPT-cGMPS is a competitive inhibitor of cGMP-dependent protein kinase (PKG) (Ki=0.5 μM). Rp-8-pCPT-cGMPS has high lipid solubility and can more easily penetrate the cell membrane and reach sufficient concentration inside the cell to inhibit cGMP-dependent protein kinase. Rp-8-pCPT-cGMPS can be used to study the activity and function of cGMP-dependent protein kinase in platelets[1].
Target Antigen
PKG
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/rp-8-pcpt-cgmps.html
Smiles
O=C(NC(N)=N1)C2=C1N(C(SC3=CC=C(Cl)C=C3)=N2)[C@H]4[C@H](O)[C@H](O[P@@]5(S)=O)[C@@H](CO5)O4
Molecular Weight
503.88
References & Citations
[1]E Butt, et al. (Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. European Journal of Pharmacology: Molecular Pharmacology 269.2 (1994): 265-268.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-137373/Rp-8-pCPT-cGMPS-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-137373/
Clinical Information
No Development Reported
CAS Number
153660-04-9
Curated Selection
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