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Rp-8-pCPT-cGMPS

Rp-8-pCPT-cGMPS is a competitive inhibitor of cGMP-dependent protein kinase (PKG) (Ki=0.5 μM) . Rp-8-pCPT-cGMPS has high lipid solubility and can more easily penetrate the cell membrane and reach sufficient concentration inside the cell to inhibit cGMP-dependent protein kinase. Rp-8-pCPT-cGMPS can be used to study the activity and function of cGMP-dependent protein kinase in platelets[1].

Product Specifications

CAS Number

[153660-04-9]

UNSPSC

12352005

Target

PKG

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/rp-8-pcpt-cgmps.html

Smiles

O=C(NC(N)=N1)C2=C1N(C(SC3=CC=C(Cl)C=C3)=N2)[C@H]4[C@H](O)[C@H](O[P@@]5(S)=O)[C@@H](CO5)O4

Molecular Formula

C16H15ClN5O6PS2

Molecular Weight

503.88

References & Citations

[1]E Butt, et al. (Rp) -8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor. European Journal of Pharmacology: Molecular Pharmacology 269.2 (1994) : 265-268.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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