Anti-UBE2A/B Antibody
Boster Bio Anti-UBE2A/B Antibody catalog # A05264. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Ubiquitin-conjugating enzyme E2 A;2.3.2.23 ; E2 ubiquitin-conjugating enzyme A; RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A; UBE2A; RAD6A
Gene Name
UBE2A
UniProt
P49459
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the C-terminal region of human UBE2A/B.
Applications
WB, IHC
Purification
Immunogen affinity purified
Form
Liquid
Function
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. .
Molecular Weight
17315 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Ubiquitin-conjugating enzyme E2 A
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