Anti-Histone deacetylase 10 HDAC10 Antibody

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.<br><br>Jenny J. Tong, Nucleic Acids Res., Mar 2002; 30: 1114 - 1123.<br>Hung-Ying Kao, J. Biol. Chem., Jan 2002; 277: 187 - 193.<br>Denise D. Fischer, J. Biol. Chem., Feb 2002; 277: 6656 - 6666.<br>Matthew H. Brush, J. Biol. Chem., Feb 2004; 279: 7685 - 7691.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) . Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.