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Anti-Kelch-like protein 3 KLHL3 Antibody

Boster Bio Anti-Kelch-like protein 3 KLHL3 Antibody (Catalog # A05117) . Tested in WB, IHC, IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.<br><br>Lai F., Genomics 66:65-75(2000).<br>Hirosawa M., DNA Res. 6:329-336(1999).<br>Ota T., Nat. Genet. 36:40-45(2004).

Synonyms

Kelch-like protein 3; KLHL3; KIAA1129

Gene Name

KLHL3

UniProt

Q9UH77

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from N-terminal of human KLHL3.

Clonality

Polyclonal

Tissue Specificity

Widely expressed. .

Applications

WB, IHC, IF

Field of Research

Cell Biology

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Form

Liquid

Function

Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR (KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation. .

Molecular Weight

64970 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05117

Product MSDS

https://www.bosterbio.com/msds?sku=A05117

Other Gene Names

Kelch-like protein 3

Subcellular Location

Cytoplasm, cytoskeleton . Cytoplasm, cytosol .

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