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Anti-PTGIS/Prostaglandin I2 Synthase Antibody

Boster Bio Anti-PTGIS/Prostaglandin I2 Synthase Antibody (Catalog # A05053-1) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).<br><br>Miyata A., Biochem. Biophys. Res. Commun. 200:1728-1734(1994).<br>Chevalier D., Hum. Genet. 108:148-155(2001).<br>Deloukas P., Nature 414:865-871(2001).

Synonyms

Prostacyclin synthase;5.3.99.4 ; Prostaglandin I2 synthase; PTGIS; CYP8, CYP8A1

Gene Name

PTGIS

UniProt

Q16647

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from Internal of human PTGIS.

Clonality

Polyclonal

Tissue Specificity

Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.

Applications

WB

Field of Research

Cancer, Cancer Metabolism, Cardiovascular, Cytochromes, Developmental Biology, Endocrine Metabolism, Hormone Biosynthesis, Immunology, Innate Immunity, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipid Signaling, Lipids/Lipoproteins, Macrophage/Inflammation, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Mitochondrial Metabolism, Pathways and Processes, Platelets, Reproduction, Signal Transduction, Signaling Pathway, Vasculature

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2) .

Molecular Weight

57104 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Prostacyclin synthase

Subcellular Location

Endoplasmic reticulum membrane; Single-pass membrane protein.

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