What is the catalog number for Anti-THOC5/Fmip Antibody?

The catalog number for Anti-THOC5/Fmip Antibody is A04619-1.

What sizes are available for Anti-THOC5/Fmip Antibody?

Anti-THOC5/Fmip Antibody is available in the following size(s): 100 µL.

Is Anti-THOC5/Fmip Antibody in stock?

Anti-THOC5/Fmip Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Where can I find the safety data sheet (SDS/MSDS) for Anti-THOC5/Fmip Antibody?

The safety data sheet for Anti-THOC5/Fmip Antibody is available here: https://www.bosterbio.com/msds?sku=A04619-1.

Anti-THOC5/Fmip Antibody

Boster Bio Anti-THOC5/Fmip Antibody (Catalog# A04619-1) . Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Synonyms

THOC5; C22orf19; KIAA0983; THO complex subunit 5 homolog; Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90

Gene Name

THOC5

UniProt

Q13769

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A peptide derived from human THOC5. Immunogen sequence location: 561 - 610

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

WB, IHC-P, IF (paraffin), ELISA

Field of Research

Immunology, Innate Immunity, Macrophage/Inflammation

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Form

Liquid

Function

Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. THOC5 in conjunction with ALYREF/THOC4 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in transcription elongation and genome stability. Involved in alternative polyadenylation site choice by recruiting CPSF6 to 5' region of target genes; probably mediates association of the TREX and CFIm complexes.