Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MARK MARK1 Antibody

Boster Bio Anti-MARK MARK1 Antibody (Catalog # A04564-1) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).<br><br>Lizcano J.M., EMBO J. 23:833-843(2004).<br>Nagase T., DNA Res. 7:143-150(2000).<br>Gregory S.G., Nature 441:315-321(2006).

Synonyms

Serine/threonine-protein kinase MARK1;2.7.11.1;2.7.11.26; MAP/microtubule affinity-regulating kinase 1; PAR1 homolog c; Par-1c; Par1c; MARK1 ; KIAA1477 , MARK

Gene Name

MARK1

UniProt

Q9P0L2

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human MARK.

Clonality

Polyclonal

Tissue Specificity

Highly expressed in heart, skeletal muscle, brain, fetal brain and fetal kidney. .

Applications

WB

Field of Research

Cytoskeleton, Cytoskeleton/ECM, Microtubules, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3) . .

Molecular Weight

89003 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04564-1

Product MSDS

https://www.bosterbio.com/msds?sku=A04564-1

Other Gene Names

Serine/threonine-protein kinase MARK1

Subcellular Location

Cell membrane ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Appears to localize to an intracellular network. .

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

C1QA CRISPR Knock Out 293T Cell Line (Human)
14240141 1x10<sup>6</sup> cells/1.0ml

C1QA CRISPR Knock Out 293T Cell Line (Human)

Ask
View Details
Pygo1 (Pygopus Homolog 1) (MaxLight 750)
MBS6270054-01 0.1 mL

Pygo1 (Pygopus Homolog 1) (MaxLight 750)

Ask
View Details
Pygo1 (Pygopus Homolog 1) (MaxLight 750)
MBS6270054-02 5x 0.1 mL

Pygo1 (Pygopus Homolog 1) (MaxLight 750)

Ask
View Details
ATP5F1 (C-12) FITC
sc-514419 FITC 200 µg/mL

ATP5F1 (C-12) FITC

Ask
View Details
Mouse HGF R/c-MET (P16056) VersaClone cDNA
RDC0681 10 µg

Mouse HGF R/c-MET (P16056) VersaClone cDNA

Ask
View Details