Anti-MAGI2 Antibody

Boster Bio Anti-MAGI2 Antibody (Catalog # A04546-1) . Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Product Specifications

Background

Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.<br><br>Florindo C.S., Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases. <br>The MGC Project Team, Genome Res. 14:2121-2127(2004). <br>Devroe E., J. Biol. Chem. 279:24444-24451(2004).

Synonyms

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2; Atrophin-1-interacting protein 1; AIP-1; Atrophin-1-interacting protein A; Membrane-associated guanylate kinase inverted 2; MAGI-2; MAGI2; ACVRINP1, AIP1, KIAA0705

Gene Name

MAGI2

UniProt

Q86UL8

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Synthesized peptide derived from internal of human MAGI2.

Clonality

Polyclonal

Tissue Specificity

Specifically expressed in brain. .

Applications

Field of Research

Neurodegenerative Disease, Neurology Process, Neuroscience

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Molecular Weight

158754 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Subcellular Location

Cytoplasm . Late endosome . Cell junction, synapse, synaptosome . Cell membrane ; Peripheral membrane protein . Localized diffusely in the cytoplasm before nerve growth factor (NGF) stimulation. Recruted to late endosomes after NGF stimulation. Membrane-associated in synaptosomes (By similarity) . .