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Anti-CHST6 Antibody

Boster Bio Anti-CHST6 Antibody (Catalog # A04511) . Tested in IF applications. This antibody reacts with Human.

Product Specifications

Background

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N-acetyllactosamine structures.<br><br>Akama T.O., Nat. Genet. 26:237-241(2000).<br>Hemmerich S., Glycobiology 11:75-87(2001).<br>Bartes A., Biochem. Biophys. Res. Commun. 282:928-933(2001).

Synonyms

Carbohydrate sulfotransferase 6;2.8.2.-; Corneal N-acetylglucosamine-6-O-sulfotransferase; C-GlcNAc6ST; hCGn6ST; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 4-beta; GST4-beta; N-acetylglucosamine 6-O-sulfotransferase 5; GlcNAc6ST-5; Gn6st-5; CHST6

Gene Name

CHST6

UniProt

Q9GZX3

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human CHST6.

Clonality

Polyclonal

Tissue Specificity

Expressed in cornea. Mainly expressed in brain. Also expressed in spinal cord and trachea. .

Applications

IF

Field of Research

Neuroscience, Organelles, Sensory System, Subcellular Markers, Tags & Cell Markers, Visual System

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunofluorescence: 1:100~1:500

Form

Liquid

Function

Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues of keratan. Mediates sulfation of keratan in cornea. Keratan sulfate plays a central role in maintaining corneal transparency. Acts on the non-reducing terminal GlcNAc of short and long carbohydrate substrates that have poly-N- acetyllactosamine structures. .

Molecular Weight

44099 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Carbohydrate sulfotransferase 6

Subcellular Location

Golgi apparatus membrane ; Single-pass type II membrane protein .

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