Anti-CABP CABP1 Antibody
Boster Bio Anti-CABP CABP1 Antibody catalog # A04165-1. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.
Product Specifications
Synonyms
Calcium-binding protein 1; CaBP1; Calbrain; Caldendrin; CABP1
Gene Name
CABP1
UniProt
Q9NZU7
Host
Rabbit
Reactivity
Rat, Mouse
Immunogen
Synthetic Peptide
Tissue Specificity
Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum.
Applications
WB, IHC
Purification
Immunogen affinity purified
Dilution
WB, 1:500-1:2000
Form
Liquid
Function
Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs) . Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity) . Inhibits TRPC5 channels. Prevents NMDA receptor- induced cellular degeneration (By similarity) . .
Molecular Weight
39838 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A04165-1
Product MSDS
https://www.bosterbio.com/msds?sku=A04165-1
Fragment
IgG
Other Gene Names
Calcium-binding protein 1
Subcellular Location
Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor; Cytoplasmic side. Golgi apparatus . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane. .
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items