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Anti-CABP CABP1 Antibody

Boster Bio Anti-CABP CABP1 Antibody catalog # A04165-1. Tested in IHC, WB applications. This antibody reacts with Mouse, Rat.

Product Specifications

Synonyms

Calcium-binding protein 1; CaBP1; Calbrain; Caldendrin; CABP1

Gene Name

CABP1

UniProt

Q9NZU7

Host

Rabbit

Reactivity

Rat, Mouse

Immunogen

Synthetic Peptide

Tissue Specificity

Retina and brain. Somatodendritic compartment of neurons. Calbrain was found exclusively in brain where it is abundant in the hippocampus, habenular area in the epithalamus and in the cerebellum.

Applications

WB, IHC

Purification

Immunogen affinity purified

Dilution

WB, 1:500-1:2000

Form

Liquid

Function

Modulates calcium-dependent activity of inositol 1,4,5- triphosphate receptors (ITPRs) . Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity) . Inhibits TRPC5 channels. Prevents NMDA receptor- induced cellular degeneration (By similarity) . .

Molecular Weight

39838 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A04165-1

Product MSDS

https://www.bosterbio.com/msds?sku=A04165-1

Fragment

IgG

Other Gene Names

Calcium-binding protein 1

Subcellular Location

Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Cell membrane ; Lipid-anchor; Cytoplasmic side. Golgi apparatus . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . L-CaBP1 is associated most likely with the cytoskeletal structures, whereas S-CaBP1 is localized at or near the plasma membrane. .
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