Fusidic acid-d6

Fusidic acid-d6 is the deuterium labeled Fusidic acid. Fusidic acid (Fusidate) a bacteriostatic antibiotic produced from the Fusidium coccineum fungus, belongs to the class of steroids. Fusidic acid has no corticosteroid effects. Fusidic acid inhibits the growth of bacteria by preventing the release of translation elongation factor G (EF-G) from the ribosome[1][2].

Product Specifications

Product Name Alternative

Fusidate-d6; SQ-16603-d6

UNSPSC

12352211

Target

Antibiotic; Bacterial

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

C[C@@H]([C@]1([H])CC[C@]([C@@](C[C@@H]/2OC(C)=O)3C)4C)[C@H](O)CC[C@]1(C)[C@]4([H])[C@H](O)C[C@@]3([H])C2=C(C(O)=O)/CC/C=C(C([2H])([2H])[2H])/C([2H])([2H])[2H]

Molecular Formula

C31H42D6O6

Molecular Weight

522.75

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Curbete MM, et al. A Critical Review of the Properties of Fusidic Acid and Analytical Methods for Its Determination. Crit Rev Anal Chem. 2016;46 (4) :352-360.|[3]Payne AJ, et al. Fusidic acid is an effective treatment against Toxoplasma gondii and Listeria monocytogenes in vitro, but not in mice. Parasitol Res. 2013;112 (11) :3859-3863.