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Anti-Shank 2 Antibody

Boster Bio Anti-Shank 2 Antibody catalog # A03782. Tested in WB applications. This antibody reacts with Human.

Product Specifications

Synonyms

SH3 and multiple ankyrin repeat domains protein 2; Shank2; Cortactin-binding protein 1; CortBP1; Proline-rich synapse-associated protein 1; SHANK2; CORTBP1, KIAA1022, PROSAP1

Gene Name

SHANK2

UniProt

Q9UPX8

Host

Rabbit

Reactivity

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human SHANK2. AA range:331-380

Tissue Specificity

Isoform 3 is present in epithelial colonic cells (at protein level) . .

Applications

WB

Purification

Immunogen affinity purified

Form

Liquid

Function

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Molecular Weight

158822 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Fragment

IgG

Other Gene Names

SH3 and multiple ankyrin repeat domains protein 2

Subcellular Location

Apical cell membrane . Cytoplasm . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, growth cone . Cell projection, dendritic spine . Colocalizes with cortactin in growth cones in differentiating hippocampal neurons. Colocalized with PDE4D to the apical membrane of colonic crypt cells (By similarity) . .

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