Anti-Shank 2 Antibody
Boster Bio Anti-Shank 2 Antibody catalog # A03782. Tested in WB applications. This antibody reacts with Human.
Product Specifications
Synonyms
SH3 and multiple ankyrin repeat domains protein 2; Shank2; Cortactin-binding protein 1; CortBP1; Proline-rich synapse-associated protein 1; SHANK2; CORTBP1, KIAA1022, PROSAP1
Gene Name
SHANK2
UniProt
Q9UPX8
Host
Rabbit
Reactivity
Human
Immunogen
The antiserum was produced against synthesized peptide derived from human SHANK2. AA range:331-380
Tissue Specificity
Isoform 3 is present in epithelial colonic cells (at protein level) . .
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.
Molecular Weight
158822 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
SH3 and multiple ankyrin repeat domains protein 2
Subcellular Location
Apical cell membrane . Cytoplasm . Cell junction, synapse . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, growth cone . Cell projection, dendritic spine . Colocalizes with cortactin in growth cones in differentiating hippocampal neurons. Colocalized with PDE4D to the apical membrane of colonic crypt cells (By similarity) . .
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