Anti-KChIP3 Antibody
Boster Bio Anti-KChIP3 Antibody catalog # A03700-1. Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Calsenilin; A-type potassium channel modulatory protein 3; DRE-antagonist modulator; DREAM; Kv channel-interacting protein 3; KChIP3; KCNIP3; CSEN, DREAM, KCHIP3
Gene Name
KCNIP3
UniProt
Q9Y2W7
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Tissue Specificity
Highly expressed in brain. Widely expressed at lower levels. Expression levels are elevated in brain cortex regions affected by Alzheimer disease. .
Applications
IHC
Purification
Immunogen affinity purified
Form
Liquid
Function
Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception (By similarity) . .
Molecular Weight
29231 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Calsenilin
Subcellular Location
Cytoplasm . Cell membrane ; Lipid-anchor . Endoplasmic reticulum . Golgi apparatus. Nucleus. Also membrane-bound, associated with the plasma membrane (PubMed:15485870) . In the presence of PSEN2 associated with the endoplasmic reticulum and Golgi. The sumoylated form is present only in the nucleus. .
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