Anti-RAP2A Antibody

Boster Bio Anti-RAP2A Antibody (Catalog# A03547) . Tested in WB application (s) . This antibody reacts with Human.

Product Specifications

Synonyms

Ras-related protein Rap-2a; RbBP-30; RAP2A

Gene Name

RAP2A

UniProt

P10114

Host

Rabbit

Reactivity

Human

Immunogen

Full length recombinant RAP2A protein

Clonality

Polyclonal

Applications

Field of Research

G Protein Signaling, Ras Family, Signal Transduction, Signaling Pathway, Small G Proteins

Purification

Protein A Chromatography

Concentration

0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

Dilution

Western blot: 1-2 µg/ml

Form

Liquid

Function

Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading. .

Molecular Weight

20615 MW

Shipping Conditions

Available

Storage Conditions

Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Fragment

Rabbit IgG

Other Gene Names

Ras-related protein Rap-2a

Subcellular Location

Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Midbody. May also localize to the Golgi (PubMed:7962206) and the gelatinase-containing granules of neutrophils (PubMed:8391995) . Colocalizes with RASGEF1B to midbody at telophase (PubMed:23894443) .