Anti-PTP zeta PTPRZ1 Antibody
Boster Bio Anti-PTP zeta PTPRZ1 Antibody catalog # A03510. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Receptor-type tyrosine-protein phosphatase zeta; R-PTP-zeta;3.1.3.48 ; Protein-tyrosine phosphatase receptor type Z polypeptide 1; Protein-tyrosine phosphatase receptor type Z polypeptide 2; R-PTP-zeta-2; PTPRZ1; HTPZP2, PTPRZ, PTPRZ2, PTPZ
Gene Name
PTPRZ1
UniProt
P23471
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PTPRZ1. AA range:122-171
Tissue Specificity
Specifically expressed in the central nervous system, where it is localized in the Purkinje cell layer of the cerebellum, the dentate gyrus, and the subependymal layer of the anterior horn of the lateral ventricle. Developmentally regulated in the brain. .
Applications
WB
Purification
Immunogen affinity purified
Form
Liquid
Function
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity) . .
Molecular Weight
254587 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A03510
Product MSDS
https://www.bosterbio.com/msds?sku=A03510
Fragment
IgG
Other Gene Names
Receptor-type tyrosine-protein phosphatase zeta
Subcellular Location
Isoform 1: Cell membrane; Single-pass type I membrane protein. Secreted . A secreted form is apparently generated by shedding of the extracellular domain. .
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