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Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody

Boster Bio Anti-Cytochrome P450 4A11/22 CYP4A11 Antibody (Catalog # A03493) . Tested in WB applications. This antibody reacts with Human.

Product Specifications

Background

Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).<br><br>Capdevila J.H., Arch. Biochem. Biophys. 409:221-227(2003).<br>Bentley D.R., Nature 441:315-321(2006).<br>Shin H.D., J. Hum. Genet. 50:259-263(2005).

Synonyms

Cytochrome P450 4A11;20-hydroxyeicosatetraenoic acid synthase;20-HETE synthase; CYP4AII; CYPIVA11; Cytochrome P-450HK-omega; Cytochrome P450HL-omega; Fatty acid omega-hydroxylase; Lauric acid omega-hydroxylase; Long-chain fatty acid omega-monooxygenase;1.14.13.205 ; CYP4A11; CYP4A2

Gene Name

CYP4A11

UniProt

Q02928

Host

Rabbit

Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human CYTOCHROME P450 4A11/22.

Clonality

Polyclonal

Tissue Specificity

Kidney and liver. .

Applications

WB

Field of Research

Cancer, Cancer Metabolism, Cardiovascular, Cytochromes, Drug Metabolism, Lipases, Lipid and Lipoprotein Metabolism, Lipid Metabolism, Lipids/Lipoproteins, Metabolic Signaling Pathway, Metabolic Signaling Pathways, Metabolism, Metabolism of Lipids and Lipoproteins, Mitochondrial, Mitochondrial Markers, Mitochondrial Metabolism, Pathways and Processes, Signal Transduction

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Western blotting: 1:500~1:3000

Form

Liquid

Function

Catalyzes the omega- and (omega-1) -hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE) . .

Molecular Weight

59348 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Cytochrome P450 4A11

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

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