Anti-Dab1 (Ab-232) Antibody
Boster Bio Anti-Dab1 (Ab-232) Antibody (Catalog # A03459-1) . Tested in IHC applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Background
The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
<br><br>Kelian Chen, et, al. (2003) J. Cell Sci ; 117: 4527 - 4536.
<br>Vera Strasser, et, al. (2004) Mol. Cell. Biol ; 24: 1378 - 1386.
<br>Izhar Ben-Shlomo, et, al. (2003) Sci. STKE ; 2003: 9.
<br>H. M. Kim, et, al. (2002) PNAS ; 99: 4020.
Gene Name
DAB1
UniProt
O75553
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peptide sequence around aa.230~234 (G-V-Y-D-V) derived from Human Dab1.
Clonality
Polyclonal
Applications
IHC
Field of Research
Signal Transduction, Vesicle Transport
Purification
Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/ml
Form
Liquid
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=A03459-1
Product MSDS
https://www.bosterbio.com/msds?sku=A03459-1
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