Anti-PARP-2 Antibody
Boster Bio Anti-PARP-2 Antibody catalog # A03270-1. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.
Product Specifications
Synonyms
Poly [ADP-ribose] polymerase 2; PARP-2; hPARP-2;2.4.2.30; ADP-ribosyltransferase diphtheria toxin-like 2; ARTD2; NAD (+) ADP-ribosyltransferase 2; ADPRT-2; Poly[ADP-ribose] synthase 2; pADPRT-2; PARP2; ADPRT2, ADPRTL2
Gene Name
PARP2
UniProt
Q9UGN5
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human PARP2. AA range:151-200
Clonality
Polyclonal
Tissue Specificity
Widely expressed, mainly in actively dividing tissues. The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low in leukocytes, colon, small intestine, prostate and thymus.
Applications
ELISA, WB
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using a epitope-specific immunogen.
Concentration
1 mg/ml
Form
Liquid
Function
Involved in the base excision repair (BER) pathway, by catalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Molecular Weight
66206 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Poly [ADP-ribose] polymerase 2
Subcellular Location
Nucleus.
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