Anti-SLC12A4/Kcc1 Antibody
Boster Bio Anti-SLC12A4/Kcc1 Antibody catalog # A02864. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
Product Specifications
Synonyms
Solute carrier family 12 member 4; Electroneutral potassium-chloride cotransporter 1; Erythroid K-Cl cotransporter 1; hKCC1; SLC12A4; KCC1
Gene Name
SLC12A4
UniProt
Q9UP95
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Synthetic Peptide
Tissue Specificity
Ubiquitous. Levels are much higher in erythrocytes from patients with Hb SC and Hb SS compared to normal AA erythrocytes. This may contribute to red blood cell dehydration and to the manifestation of sickle cell disease by increasing the intracellular concentration of HbS. Isoform 1 was not detected in circulating reticulocytes.
Applications
WB, IHC
Purification
Immunogen affinity purified
Form
Liquid
Function
Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl (-) exit in NaCl absorbing epithelia (By similarity) . Isoform 4 has no transport activity. .
Molecular Weight
120650 MW
Shipping Conditions
Available
Storage Conditions
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Fragment
IgG
Other Gene Names
Solute carrier family 12 member 4
Subcellular Location
Membrane; Multi-pass membrane protein.
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