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Anti-TTF2 FOXE1 Antibody

Boster Bio Anti-TTF2 FOXE1 Antibody (Catalog # A02831-1) . Tested in IF applications. This antibody reacts with Human, Mouse.

Product Specifications

Background

Probable transcription factor. Could be involved in thyroid gland organogenesis.<br><br>Buanne P., Genomics 51:233-242(1998).<br>Hillier L.W., Nature 424:157-164(2003).<br>The MGC Project Team; Genome Res. 14:2121-2127(2004).

Synonyms

Forkhead box protein E1; Forkhead box protein E2; Forkhead-related protein FKHL15; HFKH4; HNF-3/fork head-like protein 5; HFKL5; Thyroid transcription factor 2; TTF-2; FOXE1; FKHL15, FOXE2, TITF2, TTF2

Gene Name

FOXE1

UniProt

O00358

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Synthesized peptide derived from internal of human TTF2.

Clonality

Polyclonal

Tissue Specificity

Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.

Applications

IF

Field of Research

Domain Families, Epigenetics and Nuclear Signaling, Forkhead Box, Transcription, Transcription Factors

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Dilution

Immunofluorescence: 1:100~1:500

Form

Liquid

Function

Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression. .

Molecular Weight

38076 MW

Shipping Conditions

Available

Storage Conditions

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Other Gene Names

Forkhead box protein E1

Subcellular Location

Nucleus .

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